BAR HARBOR — The MDI Biological Laboratory will receive a grant of $456,500 over two years from the National Institutes of Health (NIH) for the study of peripheral neuropathy.
The grant from the National Institute of Neurological Disorders and Stroke will support research conducted by Assistant Professor Sandra Rieger on chemotherapy-induced peripheral neuropathy, a disabling condition causing pain, numbness, tingling and temperature sensitivity in the distal extremities. Approximately 60 to 70 percent of chemotherapy patients suffer from this condition, for which no treatments currently exist.
Her lab has identified two drug candidates with the potential to prevent or reverse the effects of sensory nerve degeneration in zebrafish. The grant funding will be used in part to assess the efficacy of the drug candidates in mammalian models.
Rieger and other scientists at the institution’s Kathryn W. Davis Center for Regenerative Biology and Medicine study a range of organisms with the ability to easily repair and regenerate lost and damaged tissues.